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VRT-043198 (Standard) [CAS 244133-31-1]
VRT-043198 (Standard) [CAS 244133-31-1]
SKU:QM-0003725
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Product Details
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Description
VRT-043198 (Standard) is the analytical standard of VRT-043198. This product is intended for research and analytical applications. VRT-043198, the agent metabolite of VX-765 (Belnacasan), is a potent, selective and blood-brain barrier permeable inhibitor of interleukin-converting enzyme/caspase-1 subfamily caspases. VRT-043198 exhibits Ki values of 0.8 nM and 0.6 nM for ICE/caspase-1 and caspase-4, respectively[1].
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CAS Number
[244133-31-1]
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Molecular Formula
C22H29ClN4O6
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Molecular Weight
480.94
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Smiles
O=C(N[C@H](C=O)CC(O)=O)[C@H]1N(C([C@H](C(C)(C)C)NC(C2=CC=C(N)C(Cl)=C2)=O)=O)CCC1
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Target
Caspase; Drug Metabolite; Reference Standards
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Shipping Conditions
Room temperature
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VRT-043198 (Standard) [CAS 244133-31-1]
VRT-043198 (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.