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VT02956 (hydrochloride)
VT02956 (hydrochloride)
SKU:QM-0067201
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Quantity
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Product Details
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Description
VT02956 is a LATS inhibitor (IC50: 0.76 nM for LATS1, 0.52 nM for LATS2) . VT02956 targets the Hippo pathway. VT02956 inhibits ESR1 expression and growth of ER+ breast cancer cell lines and patient-derived tumor organoids[1]. VT02956 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Molecular Formula
C22H24ClN5O
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Molecular Weight
409.91
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Smiles
NCC1CCN(CC1)C2=NC(C3=CC=NC=C3)=NC4=C2C=CC=C4C#CCO.[H]Cl
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Target
YAP
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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VT02956 (hydrochloride)
VT02956 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.