VU0134992 (hydrochloride) [CAS 1052515-91-9]
VU0134992 (hydrochloride) [CAS 1052515-91-9]
SKU:QM-0140572-01
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Product Details
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Description
VU0134992 hydrochloride is the first subtype-preferring, orally active and selective Kir4.1 potassium channel pore blocker, with an IC50 of 0.97 μM. VU0134992 hydrochloride is 9-fold selective for homomeric Kir4.1 over Kir4.1/5.1 concatemeric channels (IC50=9 μM) at -120 mV[1].
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CAS Number
[1052515-91-9]
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Molecular Formula
C20H32BrClN2O2
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Molecular Weight
447.84
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Smiles
O=C(NC1CC(C)(C)NC(C)(C)C1)COC2=CC=C(C(C)C)C=C2Br.[H]Cl
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Target
Potassium Channel
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Purity
98.49
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Solubility
DMSO : 250 mg/mL (ultrasonic) |H2O : 2.27 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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VU0134992 (hydrochloride) [CAS 1052515-91-9]
VU0134992 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.