VU0357017 (hydrochloride) [CAS 1135242-13-5]
VU0357017 (hydrochloride) [CAS 1135242-13-5]
SKU:QM-0155509-01
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Product Details
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Description
VU0357017 hydrochloride (CID-25010775) is a potent, selective and brain-penetrant allosteric agonist of M1 muscarinic acetylcholine receptor, with an EC50 of 477 nM. VU0357017 hydrochloride is highly selective for M1 and has no activity at M2-M5 up to the highest concentrations tested (30 μM) . VU0357017 hydrochloride can be used for the research of Alzheimer’s disease and schizophrenia[1][2][3].
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CAS Number
[1135242-13-5]
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Molecular Formula
C18H28ClN3O3
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Molecular Weight
369.89
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Smiles
O=C(N1CCC(NCCNC(C2=CC=CC=C2C)=O)CC1)OCC.[H]Cl
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Target
MAChR
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Isoform
MAChR1
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Purity
99.91
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Solubility
DMSO : 25 mg/mL (ultrasonic) |H2O : 33.33 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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VU0357017 (hydrochloride) [CAS 1135242-13-5]
VU0357017 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.