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VU0360172 (hydrochloride) [CAS 1309976-62-2]
VU0360172 (hydrochloride) [CAS 1309976-62-2]
SKU:QM-0057776-01
£301.50 GBP
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Product Details
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Description
VU0360172 hydrochloride is a potent and selective mGlu5 receptor positive allosteric modulator (PAM) with an EC50 value of 16 nM and a Ki of 195 nM, respectively. VU0360172 hydrochloride stimulates polyphosphoinositide (PI) hydrolysis in vivo, which is abrogated in mGlu5 receptors gene deleted mice[1].
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CAS Number
[1309976-62-2]
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Molecular Formula
C18H16ClFN2O
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Molecular Weight
330.78
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Smiles
O=C(C1=CN=C(C=C1)C#CC2=CC(F)=CC=C2)NC3CCC3.Cl
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Target
MGluR
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Isoform
MGluR5
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Purity
98.94
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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VU0360172 (hydrochloride) [CAS 1309976-62-2]
VU0360172 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.