VU0364770 (Standard) [CAS 61350-00-3]
VU0364770 (Standard) [CAS 61350-00-3]
SKU:QM-0001924
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Product Details
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Description
VU0364770 (Standard) is the analytical standard of VU0364770. This product is intended for research and analytical applications. VU0364770 is a selective and potent positive allosteric modulator (PAM) of mGlu4. VU0346770 exhibits EC50s of 290 nM and 1.1 μM at rat mGlu4 and human mGlu4 receptor, respectively. VU0364770 exhibits antagonist activity at mGlu5 with a potency of 17.9 μM and PAM activity at mGlu6 with a potency of 6.8 μM. VU0364770 also possesses activity at MAO with Ki values of 8.5 and 0.72 μM for human MAO-A and human MAO-B, respectively[1].
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CAS Number
[61350-00-3]
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Molecular Formula
C12H9ClN2O
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Molecular Weight
232.67
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Smiles
O=C(C1=NC=CC=C1)NC2=CC=CC(Cl)=C2
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Target
MGluR; Reference Standards
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Shipping Conditions
Room temperature
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VU0364770 (Standard) [CAS 61350-00-3]
VU0364770 (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.