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Wy-45494 (hydrochloride) [CAS 93413-90-2]

Wy-45494 (hydrochloride) [CAS 93413-90-2]

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QM-0129850-01

£57.09 GBP
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Product Details

  • Description

    Wy-45494 hydrochloride (N-Desmethyl Venlafaxine hydrochloride; Wy 45494) is a minor active metabolite of the selective norepinephrine and serotonin reuptake inhibitor (SNRI) venlafaxine. It is formed from venlafaxine via the cytochrome P450 (CYP) isomer CYP3A4.2. Wy-45494 hydrochloride inhibits norepinephrine and serotonin reuptake in rat synaptosomal preparations (IC50s of 4.7 and 1.6 μM, respectively) . In vivo, Wy-45494 hydrochloride reversed reserpine-induced hypothermia in mice at a minimum effective dose (MED) of 10 mg/kg.

  • CAS Number

    [93413-90-2]

  • Molecular Formula

    C16H26ClNO2

  • Molecular Weight

    299.84

  • Smiles

    OC1(C(C2=CC=C(OC)C=C2)CNC)CCCCC1.[H]Cl

  • Target

    Serotonin Transporter

  • Purity

    99.65

  • Solubility

    DMSO : 116.67 mg/mL (ultrasonic)

  • Storage Conditions

    Store at room temperature 3 years

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H336

  • Precautions

    H336
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Variant Variant total Quantity Price Variant total
1 mgQM-0129850-01
1 mgQM-0129850-01
£57.09/ea		 £0.00
£57.09/ea £0.00
5 mgQM-0129850-02
5 mgQM-0129850-02
£124.00/ea		 £0.00
£124.00/ea £0.00
10 mgQM-0129850-03
10 mgQM-0129850-03
£212.81/ea		 £0.00
£212.81/ea £0.00
25 mgQM-0129850-04
25 mgQM-0129850-04
£395.06/ea		 £0.00
£395.06/ea £0.00
50 mgQM-0129850-05
50 mgQM-0129850-05
£602.83/ea		 £0.00
£602.83/ea £0.00
100 mgQM-0129850-06
100 mgQM-0129850-06
£928.45/ea		 £0.00
£928.45/ea £0.00
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Wy-45494 (hydrochloride) [CAS 93413-90-2]

Wy-45494 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.