Wy-45494 (hydrochloride) (Standard) [CAS 93413-90-2]
Wy-45494 (hydrochloride) (Standard) [CAS 93413-90-2]
SKU:QM-0129392-01
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Product Details
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Description
Wy-45494 (hydrochloride) (Standard) is the analytical standard of Wy-45494 (hydrochloride) . This product is intended for research and analytical applications. Wy-45494 hydrochloride (N-Desmethyl Venlafaxine hydrochloride; Wy 45494) is a minor active metabolite of the selective norepinephrine and serotonin reuptake inhibitor (SNRI) venlafaxine. It is formed from venlafaxine via the cytochrome P450 (CYP) isomer CYP3A4.2. Wy-45494 hydrochloride inhibits norepinephrine and serotonin reuptake in rat synaptosomal preparations (IC50s of 4.7 and 1.6 μM, respectively) . In vivo, Wy-45494 hydrochloride reversed reserpine-induced hypothermia in mice at a minimum effective dose (MED) of 10 mg/kg.
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CAS Number
[93413-90-2]
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Molecular Formula
C16H26ClNO2
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Molecular Weight
299.84
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Smiles
OC1(C(C2=CC=C(OC)C=C2)CNC)CCCCC1.[H]Cl
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Target
Reference Standards; Serotonin Transporter
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Purity
99.85
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Storage Conditions
4°C, sealed storage, away from light and moisture
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Shipping Conditions
Blue Ice
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Hazard Statement
H336
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Precautions
H336
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Wy-45494 (hydrochloride) (Standard) [CAS 93413-90-2]
Wy-45494 (hydrochloride) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.