Xaliproden (hydrochloride) [CAS 90494-79-4]
Xaliproden (hydrochloride) [CAS 90494-79-4]
SKU:QM-0148831-01
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Product Details
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Description
Xaliproden hydrochloride (SR57746A) is a potent, selective and orally active agonist of 5-HT1A receptor, shows a high affinity for 5-HT1A specific binding sites in the rat hippocampus (IC50=3 nM) . Xaliproden hydrochloride is also a selective antagonist of dopamine D2 receptor, has moderate affinity (IC50=0.1-1 μM) . Xaliproden hydrochloride exhibits anti-depression and anti-anxiety effects, and it may possess therapeutic potential for the research of neurodegenerative diseases[1][2][3].
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CAS Number
[90494-79-4]
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Molecular Formula
C24H23ClF3N
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Molecular Weight
417.89
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Smiles
FC(C1=CC(C2=CCN(CCC3=CC=C4C=CC=CC4=C3)CC2)=CC=C1)(F)F.[H]Cl
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Target
5-HT Receptor; Dopamine Receptor
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Isoform
5-HT1 Receptor; D2 Receptor; mLAG-3
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Concentration
10mM
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Purity
98.57
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Solubility
DMSO : 33.33 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302
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Precautions
H302
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Xaliproden (hydrochloride) [CAS 90494-79-4]
Xaliproden (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.