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XE991 dihydrochloride [CAS 122955-13-9]
XE991 dihydrochloride [CAS 122955-13-9]
SKU:QM-0136128-01
£200.66 GBP
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Product Details
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Description
XE991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC50s of 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively[1].
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CAS Number
[122955-13-9]
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Molecular Formula
C26H22Cl2N2O
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Molecular Weight
449.37
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Smiles
O=C1C2=C(C=CC=C2)C(CC3=CC=NC=C3)(CC4=CC=NC=C4)C5=CC=CC=C15.Cl.Cl
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Target
Potassium Channel
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Concentration
10mM
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Purity
99.63
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Solubility
DMSO : 7.14 mg/mL (ultrasonic) |H2O : 11.11 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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XE991 dihydrochloride [CAS 122955-13-9]
XE991 dihydrochloride is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.