Xylitol-13C5
Xylitol-13C5
SKU:QM-0054351
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Product Details
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Description
Xylitol-13C5 (Xylite-13C5) is the 13C-labeled Xylitol. Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell proliferation. It induces autophagy (Autophagy) and cell death in A549 cells by activating the autophagy signaling pathway, as evidenced by the increased expression of LC3-II and Atg5-Atg12 upon Xylitol treatment. Additionally, Xylitol inhibits acetaldehyde production by Candida species, thereby reducing their carcinogenic potential. In vivo, Xylitol induces alterations in the gut microbiota of mice, which may enhance cholesterol accumulation and upregulate hepatic ChREBP, while also slowing tumor growth in the B16F10 melanoma C57BL/6 mouse model[1][2][3][4].
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Molecular Formula
13C5H12O5
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Molecular Weight
157.11
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Smiles
O[13CH2][13C@H](O)[13C@@H](O)[13C@H](O)[13CH2]O
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Target
Atg7; Atg8/LC3; Autophagy; Bacterial; Endogenous Metabolite; Isotope-Labeled Compounds
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Shipping Conditions
Room temperature
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Xylitol-13C5
Xylitol-13C5 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.