Xylitol [CAS 87-99-0]
Xylitol [CAS 87-99-0]
SKU:QM-0162841-01
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Product Details
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Description
Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell proliferation. It induces autophagy (Autophagy) and cell death in A549 cells by activating the autophagy signaling pathway, as evidenced by the increased expression of LC3-II and Atg5-Atg12 upon Xylitol treatment. Additionally, Xylitol inhibits acetaldehyde production by Candida species, thereby reducing their carcinogenic potential. In vivo, Xylitol induces alterations in the gut microbiota of mice, which may enhance cholesterol accumulation and upregulate hepatic ChREBP, while also slowing tumor growth in the B16F10 melanoma C57BL/6 mouse model[1][2][3][4].
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CAS Number
[87-99-0]
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Molecular Formula
C5H12O5
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Molecular Weight
152.15
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Smiles
OC[C@@H](O)[C@H](O)[C@@H](O)CO
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Target
Atg7; Atg8/LC3; Autophagy; Bacterial; Endogenous Metabolite
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Isoform
Human Endogenous Metabolite
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Purity
99.87
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Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 110 mg/mL (ultrasonic)
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Storage Conditions
Store at room temperature 3 years
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Xylitol [CAS 87-99-0]
Xylitol is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.