Y-27632 (Standard) [CAS 146986-50-7]
Y-27632 (Standard) [CAS 146986-50-7]
SKU:QM-0001993
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Product Details
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Description
Y-27632 (Standard) is the analytical standard of Y-27632. This product is intended for research and analytical applications. Y-27632 is an orally active, ATP-competitive inhibitor of ROCK-I and ROCK-II, with Kis of 220 and 300 nM, respectively. Y-27632 attenuates Doxorubicin-induced apoptosis of human cardiac stem cells. Y-27632 also suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells. Y-27632 primes human induced pluripotent stem cells (hIPSCs) to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation[1][2][3][4][5][6][7].
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CAS Number
[146986-50-7]
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Molecular Formula
C14H21N3O
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Molecular Weight
247.34
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Smiles
O=C([C@@H]1CC[C@]([C@H](N)C)([H])CC1)NC2=CC=NC=C2
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Target
Apoptosis; Organoid; Reference Standards; ROCK
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Shipping Conditions
Room temperature
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Y-27632 (Standard) [CAS 146986-50-7]
Y-27632 (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.