(Z) -Onjisaponin B [CAS 162681-53-0]
(Z) -Onjisaponin B [CAS 162681-53-0]
SKU:QM-0024189
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Product Details
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Description
(Z) -Onjisaponin B ((Z) -Senegin III) is a derivative of Onjisaponin B. Onjisaponin B is an orally active natural product derived from Polygala tenuifolia. Onjisaponin B inhibits NF-κB p65. Onjisaponin B enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin. Onjisaponin B reduces β-amyloid (Aβ) production. Onjisaponin B reduces radiation-induced cell apoptosis. Onjisaponin B has anti-oxidant and anti-inflammatory activities. Onjisaponin B can be used for neurological disease and radiation injury study, and its metabolite tenuifolin (TF) can enter the brain through the BBB[1].
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CAS Number
[162681-53-0]
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Molecular Formula
C75H112O35
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Molecular Weight
1573.67
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Smiles
OC[C@]12[C@]3([C@@](CC=C1[C@@]4([H])[C@@](CC2)(CCC(C)(C4)C)C(O[C@H]5[C@@H]([C@H]([C@H]([C@H](O5)C)OC(/C=C\C6=CC=C(C=C6)OC)=O)O[C@H]7[C@@H]([C@@H]([C@H]([C@@H](O7)C)O)O)O)O[C@H]8[C@@H]([C@@H]([C@H]([C@@H](O8)C)O[C@H]9[C@@H]([C@H]([C@@H](CO9)O[C@@H]%10O[C@@H]([C@@H]([C@@H]([C@H]%10O)O)O)CO)O)O)O)O)=O)([H])[C@@]%11([C@@]([C@@](C)([C@H]([C@H](C%11)O)O[C@@H]%12O[C@@H]([C@H]([C@@H]([C@H]%12O)O)O)CO)C(O)=O)([H])CC3)C)C
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Target
Drug Derivative
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Shipping Conditions
Room temperature
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(Z) -Onjisaponin B [CAS 162681-53-0]
(Z) -Onjisaponin B is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.