(Z) -Pitavastatin (calcium) [CAS 1159588-21-2]
(Z) -Pitavastatin (calcium) [CAS 1159588-21-2]
SKU:QM-0145062-01
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Product Details
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Description
(Z) -Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin calcium inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells[1].
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CAS Number
[1159588-21-2]
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Molecular Formula
C25H24FNO4.1/2Ca
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Molecular Weight
440.49
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Smiles
FC(C=C1)=CC=C1C2=C(/C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)C(C3CC3)=NC4=C2C=CC=C4.[1/2].[Ca+2]
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Target
HMG-CoA Reductase (HMGCR)
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Purity
99.63
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Solubility
H2O : 9.09 mg/mL (ultrasonic; adjust pH to 2 with 1 M HCL; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H361, H362
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Precautions
H302, H361, H362
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(Z) -Pitavastatin (calcium) [CAS 1159588-21-2]
(Z) -Pitavastatin (calcium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.