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Zorifertinib (hydrochloride) [CAS 1626387-81-2]
Zorifertinib (hydrochloride) [CAS 1626387-81-2]
SKU:QM-0073987
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Product Details
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Description
Zorifertinib (AZD3759) hydrochloride is a potent, orally active, central nervous system-penetrant, EGFR inhibitor (IC50s: 0.3, 0.2, and 0.2 nM for EGFRwt, EGFRL858R, and EGFRexon 19Del, respectively) . Zorifertinib hydrochloride induces cancer cell apoptosis. Zorifertinib hydrochloride has antitumor activity, and can be used for NSCLC, HCC etc. research[1][2].
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CAS Number
[1626387-81-2]
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Molecular Formula
C22H24Cl2FN5O3
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Molecular Weight
496.36
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Smiles
ClC1=CC=CC(NC2=NC=NC3=CC(OC)=C(OC(N4[C@H](C)CN(C)CC4)=O)C=C23)=C1F.Cl
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Target
Apoptosis; EGFR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Zorifertinib (hydrochloride) [CAS 1626387-81-2]
Zorifertinib (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.