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α5β1 integrin agonist-1 [CAS 2756557-83-0]

α5β1 integrin agonist-1 [CAS 2756557-83-0]

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QM-0146845-01

£476.46 GBP
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Product Details

  • Description

    α5β1 integrin agonist-1 is an α5β1 integrin agonist, with an EC50 of 1.5 nM. α5β1 integrin agonist-1 inhabits α4β1 integrin (IC50 = 2.99 μM) in Jurkat/VCAM-1 adhesion assayα5β1 integrin agonist-1 induces concentration-dependent apoptosis and activates the caspase 3/7 pathway in α5β1 integrin-expressing K562 cancer cells. α5β1 integrin agonist-1 can be used for the study of cancer[1].

  • CAS Number

    [2756557-83-0]

  • Molecular Formula

    C24H26FN5O9

  • Molecular Weight

    547.49

  • Smiles

    OC(C[C@H]1N(C([C@]1([H])[C@@H](C)OC(CCNC(CN2C(NC(C(F)=C2)=O)=O)=O)=O)=O)C(NC3=C(C=CC=C3)C)=O)=O

  • Target

    Apoptosis; Caspase; Integrin

  • Isoform

    α4β1; α5β1

  • Purity

    99.67

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
1 mgQM-0146845-01
1 mgQM-0146845-01
£476.46/ea		 £0.00
£476.46/ea £0.00
5 mgQM-0146845-02
5 mgQM-0146845-02
£1,116.77/ea		 £0.00
£1,116.77/ea £0.00
10 mM - 1 mLQM-0146845-03
10 mM - 1 mLQM-0146845-03
£1,335.47/ea		 £0.00
£1,335.47/ea £0.00
10 mgQM-0146845-04
10 mgQM-0146845-04
£1,870.07/ea		 £0.00
£1,870.07/ea £0.00
25 mgQM-0146845-05
25 mgQM-0146845-05
£3,815.28/ea		 £0.00
£3,815.28/ea £0.00
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α5β1 integrin agonist-1 [CAS 2756557-83-0]

α5β1 integrin agonist-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.