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Bax agonist 1 [CAS 18304-79-5]
Bax agonist 1 [CAS 18304-79-5]
SKU:QM-0124795
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Product Details
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Description
Bax agonist 1 (compound SMBA2) is a Bax agonist (Ki=57.2 nM) . Bax agonist 1 induces Bax conformational changes by blocking S184 phosphorylation, promoting Bax insertion into the mitochondrial membrane and forming Bax oligomers, which induce cytochrome c release and apoptosis in malignant cancer cells expressing Bax. Bax agonist 1 can be used in lung cancer research[1].
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CAS Number
[18304-79-5]
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Molecular Formula
C8H16N4
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Molecular Weight
168.24
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Smiles
N12CN(CC2)CN(C3)CCN3C1
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Target
Apoptosis; Bcl-2 Family
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Isoform
Bax
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Shipping Conditions
Room temperature
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Bax agonist 1 [CAS 18304-79-5]
Bax agonist 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.