1
/
of
1
VEGFR/PARP-IN-1 [CAS 3010256-54-6]
VEGFR/PARP-IN-1 [CAS 3010256-54-6]
SKU:QM-0072134
Price on request
Quantity
Request quote or documents
![VEGFR/PARP-IN-1 [CAS 3010256-54-6]](http://quantimol.com/cdn/shop/files/quantimol-021.png?v=1773515276&width=1445)
Product Details
-
Description
VEGFR/PARP-IN-1 (Compound 14b) is a VEGFR/PARP dual inhibitor (IC50s: 191 nM and 60.9 nM respectively) . VEGFR/PARP-IN-1 inhibits DNA damage repair, induces cell apoptosis, and arrests cell in the G2/M phase. VEGFR/PARP-IN-1 has good antiproliferative efficacy against BRCA wild-type breast cancer cells (IC50: 4.1 and 3.5 μM for MDA-MB-231 and MCF-7 cells) . VEGFR/PARP-IN-1 is an antitumor and anti-metastasis agent[1].
-
CAS Number
[3010256-54-6]
-
Molecular Formula
C29H27N9O
-
Molecular Weight
517.58
-
Smiles
NC(C1=CC=CC2=C1N=C(N2)C3=C(C=CC(NC4=NC=CC(N(C)C5=CC6=NN(C(C)=C6C=C5)C)=N4)=C3)C)=O
-
Target
Apoptosis; PARP; VEGFR
-
Solubility
10 mM in DMSO
-
Shipping Conditions
Room temperature
Related Products
- QM-0166349 USP53, Human
- QM-0135596 WRAP53 Human Pre-designed siRNA Set A
- QM-0130847 TRAILR4/TNFRSF10D, Rhesus Macaque (HEK293, Fc)
- QM-0122122 Yp537 [CAS 166664-90-0]
- QM-0106903 Tumor targeted pro-apoptotic peptide [CAS 1926163-30-5]
- QM-0106332 YO-PRO-1/PI Apoptosis and Necrosis Detection Kit
- QM-0104587 Trp53 Mouse Pre-designed siRNA Set A
- QM-0096053 USP53, Human (His, GST)
- QM-0072756 Tubulin/PARP-IN-1
- QM-0087120 USP53 Human Pre-designed siRNA Set A
Other industry favorites
- QM-0166349 USP53, Human
- QM-0135596 WRAP53 Human Pre-designed siRNA Set A
- QM-0025311 TP53 neoepitope [CAS 151808-74-1]
- QM-0024921-01 ReACp53 scrambled peptide (TFA)
- QM-0190917-01 Uricase, Bacillus fastidious [CAS 9002-12-4]
- QM-0161805-01 VF 647A-Annexin V-PI Apoptosis Detection Kit
VEGFR/PARP-IN-1 [CAS 3010256-54-6]
VEGFR/PARP-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.