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Fasudil (dihydrochloride) [CAS 203911-27-7]

Fasudil (dihydrochloride) [CAS 203911-27-7]

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SKU:QM-0057347-01

£94.75 GBP
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  • Description

    Fasudil (HA-1077; AT877) dihydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil dihydrochloride is also a potent Ca2+ channel antagonist and vasodilator[1][2][3].

  • CAS Number

    [203911-27-7]

  • Molecular Formula

    C14H19Cl2N3O2S

  • Molecular Weight

    364.29

  • Smiles

    O=S(C1=CC=CC2=C1C=CN=C2)(N3CCNCCC3)=O.[H]Cl.[H]Cl

  • Target

    Autophagy; Calcium Channel; HIV; PKA; PKC; ROCK

  • Isoform

    PKA; PKC; ROCK1; ROCK2

  • Purity

    99.98

  • Solubility

    DMSO : 20.83 mg/mL (ultrasonic) |H2O : 100 mg/mL

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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25 mgQM-0057347-01
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50 mgQM-0057347-02
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100 mgQM-0057347-03
100 mgQM-0057347-03
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Fasudil (dihydrochloride) [CAS 203911-27-7]

Fasudil (dihydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.