Fasudil (Hydrochloride) [CAS 105628-07-7]
Fasudil (Hydrochloride) [CAS 105628-07-7]
SKU:QM-0083283-01
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Product Details
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Description
Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil Hydrochloride is also a potent Ca2+ channel antagonist and vasodilator[1][2][3].
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CAS Number
[105628-07-7]
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Molecular Formula
C14H18ClN3O2S
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Molecular Weight
327.83
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Smiles
O=S(C1=CC=CC2=C1C=CN=C2)(N3CCNCCC3)=O.Cl[H]
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Target
Autophagy; Calcium Channel; HIV; PKA; PKC; ROCK
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Isoform
PKA; PKC; ROCK1; ROCK2
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Concentration
10mM
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Purity
99.97
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Solubility
DMSO : ≥ 31 mg/mL|H2O : 55 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302
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Precautions
H302
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Fasudil (Hydrochloride) [CAS 105628-07-7]
Fasudil (Hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.