Ferroptosis-IN-17
Ferroptosis-IN-17
SKU:QM-0009385
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Product Details
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Description
Ferroptosis-IN-17 (Compound 18) is a ferroptosis (Ferroptosis) inhibitor with an EC50 value of 0.57 μM. Ferroptosis-IN-17 reduces intracellular ferrous ion accumulation, lipid peroxidation, and effectively restores the levels of glutathione (GSH) and glutathione peroxidase 4 (GPX4) . Ferroptosis-IN-17 shows good solubility and significant metabolic stability in rat plasma. Ferroptosis-IN-17 is promising for research in tumor suppression, neurodegenerative diseases, and cardiovascular diseases[1].
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Molecular Formula
C21H26N4O5S
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Molecular Weight
446.52
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Smiles
O=C(NCC)C1=CC=C(NC2CCCCC2)C(NS(=O)(C3=CC=C([N+]([O-])=O)C=C3)=O)=C1
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Target
Ferroptosis; Glutathione Peroxidase
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Isoform
GPX4
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Shipping Conditions
Room temperature
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Ferroptosis-IN-17
Ferroptosis-IN-17 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.
Review the GPX4–glutathione axis, lipid-peroxidation readouts, and validation controls used in ferroptosis research. Explore GPX4 and ferroptosis research ↗