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Ferroptosis-IN-20
Ferroptosis-IN-20
SKU:QM-0013710
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Product Details
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Description
Ferroptosis-IN-20 (Compound 34a) is a Ferroptosis inhibitor (EC50: 24.2 nM) targeting voltage-dependent anion channel (VDAC). Ferroptosis-IN-20 inhibits VDAC oligomerization and lipid peroxidation. Ferroptosis-IN-20 reduces content of ROS, attenuates TFR1-mediated iron uptake, inhibits Fe2+ level and restores glutathione (GSH) level. Ferroptosis-IN-20 alleviates Folic acid -induced acute kidney injury (AKI).
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Molecular Formula
C32H29FN2O4
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Molecular Weight
524.58
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Smiles
COC1=C(C=C(C2=C1CN3C(C4=CC5=C(C=C4CC3)OCO5)C2)NC6=CC=CC(C7=CC=C(C=C7)F)=C6)OC
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Target
Ferroptosis; Reactive Oxygen Species (ROS) ; VDAC
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Shipping Conditions
Room temperature
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Ferroptosis-IN-20
Ferroptosis-IN-20 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.