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P53 Activator 13
P53 Activator 13
SKU:QM-0114236
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Product Details
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Description
P53 Activator 13 (compound 11) is a 6mA methyltransferase CamA inhibitor and a p53 activator. p53 Activator 13 intercalates into CamA-bound DNA via the minor groove, causing a conformational shift that moves the catalytic domain away from the DNA and elicits DNA damage response via p53 activation. p53 Activator 13 can be utilized in cancer research[1].
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Molecular Formula
C33H35N9O
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Molecular Weight
573.69
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Smiles
O=C(NC1=CC(CN2CCN(C)CC2)=CC(NC3=NC(N)=NC(C)=C3)=C1)C4=CC=CC(NC5=CC=NC6=C5C=CC=C6)=C4
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Target
DNA Methyltransferase; MDM-2/p53
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Shipping Conditions
Room temperature
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P53 Activator 13
P53 Activator 13 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.