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P53 Activator 15 [CAS 3069395-29-2]

P53 Activator 15 [CAS 3069395-29-2]

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SKU:QM-0013042

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  • Description

    P53 Activator 15 is an orally active p53 Y220C activator. p53 Activator 15 enhances the DNA binding of p53 Y220C (SC50 = 0.58 nM) and significantly inhibits NUGC-3 cell proliferation. p53 Activator 15 effectively inhibits tumor growth in NUGC-3 xenograft mouse and rat models. p53 Activator 15 can be used to study gastric cancer[1].

  • CAS Number

    [3069395-29-2]

  • Molecular Formula

    C27H27D3F4N6O4S

  • Molecular Weight

    613.64

  • Smiles

    O=C(NS(C)(=O)=O)C1=CC=C(NCC#CC2=C(N3C=CC=C(C3=C2)N[C@@H]4CCN(C[C@@H]4F)C)CC(F)(F)F)C(OC([2H])([2H])[2H])=N1

  • Target

    MDM-2/p53

  • Shipping Conditions

    Room temperature

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P53 Activator 15 [CAS 3069395-29-2]

P53 Activator 15 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.