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P53 Activator 7 [CAS 2849340-59-4]

P53 Activator 7 [CAS 2849340-59-4]

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SKU:QM-0149687-01

£426.65 GBP
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  • Description

    P53 Activator 7 is a p53 mutation Y220C (MDM-2/p53) activator with an EC50 of 104 nM. p53 Activator 7 can bind to p53 mutant and restore its ability to bind DNA (WO2022213975A1; Example B-1) [1]. p53 Activator 7 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

  • CAS Number

    [2849340-59-4]

  • Molecular Formula

    C27H32F3N4OP

  • Molecular Weight

    516.54

  • Smiles

    FC(F)(F)CN1C2=C(C(NC3CCN(CC3)C)=CC=C2)C=C1C#CCNC4=CC=C(P(C)(C)=O)C=C4

  • Target

    MDM-2/p53

  • Purity

    98.52

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture and light)

  • Shipping Conditions

    Room Temperature

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Variant Variant total Quantity Price Variant total
1 mgQM-0149687-01
1 mgQM-0149687-01
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5 mgQM-0149687-02
5 mgQM-0149687-02
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10 mM - 1 mLQM-0149687-03
10 mM - 1 mLQM-0149687-03
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10 mgQM-0149687-04
10 mgQM-0149687-04
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P53 Activator 7 [CAS 2849340-59-4]

P53 Activator 7 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.