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PARP-1-IN-13 [CAS 2999661-74-2]
PARP-1-IN-13 [CAS 2999661-74-2]
SKU:QM-0071574
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Product Details
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Description
PARP-1-IN-13 (Compound 19c) is a PARP-1 inhibitor (IC50: 26 nM) . PARP-1-IN-13 inhibits DNA single-strand breakage repair and aggravates DNA double-strand breakage. PARP-1-IN-13 promotes the apoptosis of cancer cells through the mitochondrial apoptosis pathway[1].
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CAS Number
[2999661-74-2]
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Molecular Formula
C20H17N5O2S
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Molecular Weight
391.45
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Smiles
O=C1NC(C2=CC=C(/C=N/NC(NCC)=S)C=C2)=NC3=C1OC4=C3C=CC=C4
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Target
PARP
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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PARP-1-IN-13 [CAS 2999661-74-2]
PARP-1-IN-13 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.