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PARP1-IN-15
PARP1-IN-15
SKU:QM-0071661
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Product Details
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Description
PARP1-IN-15 (Compound 6) is a PARP1 inhibitor. PARP1-IN-15 inhibits tankyrase (TNKS) and facilitates DNA double-strand breaks damage. PARP1-IN-15 induces tumor cell apoptosis. PARP1-IN-15 has anti-cancer activity in triple-negative breast cancer (TNBC) cells and TNBC patient-derived organoids. PARP1-IN-15 can be used for research of TNBC with or without BRCA1 mutations[1].
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Molecular Formula
C16H12N2O2
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Molecular Weight
264.28
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Smiles
O=C1NC(/C=C/C2=CC=C(O)C=C2)=NC3=CC=CC=C31
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Target
Apoptosis; PARP
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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PARP1-IN-15
PARP1-IN-15 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.