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PARP1-IN-16
PARP1-IN-16
SKU:QM-0072297
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Product Details
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Description
PARP1-IN-16 (compound 12a) is a potent PARP1 inhibitor, with an IC50 of 1.89 nM. PARP1-IN-16 can arrest the cell cycle in S phase and induce apoptosis in HCT-116 cells[1].
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Molecular Formula
C40H34FN7O5
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Molecular Weight
711.74
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Smiles
FC(C=CC(CC1=NNC(C2=CC=CC=C21)=O)=C3)=C3C(N4CCN(CC4)C(CCCO/N=C5/C(NC6=CC=CC=C65)=C7C8=C(NC\7=O)C=CC=C8)=O)=O
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Target
Apoptosis; PARP
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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PARP1-IN-16
PARP1-IN-16 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.