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PARPYnD [CAS 2561483-27-8]

PARPYnD [CAS 2561483-27-8]

Size

QM-0066353-01

£244.40 GBP
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Product Details

  • Description

    PARPYnD is a PARP enzyme photoaffinity probe (AfBP) based on the triple PARP1/2/6 inhibitor AZ9482 , which induces breast cancer Formation of multipolar spindles (MPS) in cells. PARPYnD inhibits PAPR wih IC50 of 38 nM (PARP1), 6 nM (PARP2), 230 nM (PARP6), respectively. PARPYnD enriches recombinant PARP6 incorporated into cell lysates and inhibits PARP6 in cell-free assays, but it does not label PARP6 in intact cells[1].

  • CAS Number

    [2561483-27-8]

  • Molecular Formula

    C34H31N9O3

  • Molecular Weight

    613.67

  • Smiles

    N#CC1=CC(NC(CCC2(CCC#C)N=N2)=O)=CN=C1N3CCN(CC3)C(C4=CC=CC(CC5=NNC(C6=C5C=CC=C6)=O)=C4)=O

  • Target

    PARP

  • Isoform

    PARP1; PARP2

  • Purity

    98.86

  • Solubility

    DMSO : 5 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years (Powder)

  • Shipping Conditions

    Blue Ice

  • Hazard Statement

    H228, H315, H319

  • Precautions

    H228, H315, H319
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Variant Variant total Quantity Price Variant total
1 mgQM-0066353-01
1 mgQM-0066353-01
£144.00
£244.40/ea
 £0.00
£144.00
£244.40/ea
 £0.00
5 mgQM-0066353-02
5 mgQM-0066353-02
£358.20
£533.57/ea
 £0.00
£358.20
£533.57/ea
 £0.00
10 mgQM-0066353-03
10 mgQM-0066353-03
£571.50
£821.52/ea
 £0.00
£571.50
£821.52/ea
 £0.00
25 mgQM-0066353-04
25 mgQM-0066353-04
£1,139.40
£1,588.19/ea
 £0.00
£1,139.40
£1,588.19/ea
 £0.00
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PARPYnD [CAS 2561483-27-8]

PARPYnD is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.