TRAIL/TNFSF10, Human
TRAIL/TNFSF10, Human
SKU:QM-0204538-01
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Product Details
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Description
TRAIL Protein (TNFSF10), a member of the TNF superfamily, is a type II transmembrane protein. TRAIL Protein mainly interacts with TRAIL-R1 and TRAIL-R2, and induces apoptosis in tumor or infected cells. TRAIL Protein also binds with DR4, DR5, and OPG. TRAIL Protein can recruit FADD and further recruit and activates caspase-8 after binding to DR4 or DR5. Besides, TRAIL may also trigger nonapoptotic signaling through activating pro-inflammatory pathways[1][2]. TRAIL protein is mainly expressed on surface of immune cells, such as cytotoxic T cells and natural killer (NK) cell[1]. TRAIL/TNFSF10 Protein, Human is a recombinant human TRAIL (V114-G281) without any tag, which is expressed in E. coli.
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Molecular Formula
8743 (Gene_ID) P50591 (V114-G281) (Accession)
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Smiles
VRERGPQRVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLYSIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG
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Purity
95
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Storage Conditions
Stored at -20°C for 2 years
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Shipping Conditions
Room temperature in continental US; may vary elsewhere.
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TRAIL/TNFSF10, Human
TRAIL/TNFSF10, Human is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.