Tubulin-IN-62
Tubulin-IN-62
SKU:QM-0015976
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Product Details
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Description
Tubulin-IN-62 is a tubulin inhibitor targeting the colchicine-binding site. Tubulin-IN-62 exhibits IC50 values of 17.2 nM and 19.3 nM against SKOV3 and HCC827 cells, respectively. Tubulin-IN-62 inhibits microtubule polymerization, arrests the cell cycle at the G2/M phase, and induces apoptosis. Tubulin-IN-62 demonstrates significant antitumor efficacy in vivo with good tolerability. Tubulin-IN-62 can be used in ovarian cancer and non-small cell lung cancer (NSCLC) research[1].
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Molecular Formula
C21H23N5O3
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Molecular Weight
393.44
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Smiles
CC1=CC(C(N2)=C[C@@H](C3=CC(OC)=C(OC)C(OC)=C3)N4C2=NN=N4)=CC(C)=C1
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Target
Apoptosis; Microtubule/Tubulin; Phosphatase
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Shipping Conditions
Room temperature
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Tubulin-IN-62
Tubulin-IN-62 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.