Tubulin/LSD1-IN-1
Tubulin/LSD1-IN-1
SKU:QM-0013784
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Product Details
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Description
Tubulin/LSD1-IN-1 is an effective dual inhibitor of Tubulin polymerization and LSD1 (IC50 = 1.72 μM) . Tubulin/LSD1-IN-1 has broad-spectrum antiproliferative activity against cancer cell lines. Tubulin/LSD1-IN-1 inhibits tubulin polymerization by targeting colchicine binding sites, thereby disrupting the microtubule network in gastric cancer cells. Tubulin/LSD1-IN-1 increases the methylation levels of H3K4me1/2 and H3K9me2/3, thereby achieving epigenetic regulation. Tubulin/LSD1-IN-1 induces G2/M arrest, promotes apoptosis, and effectively inhibits colony formation of gastric cancer cells[1].
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Molecular Formula
C30H40N6O6S2
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Molecular Weight
644.81
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Smiles
S=C(N1CCN(C(C)C)CC1)SCC2=CN(CC(N(CC3=CC=C(OC)C(O)=C3)C4=CC(OC)=C(OC)C(OC)=C4)=O)N=N2
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Target
Apoptosis; Bcl-2 Family; Caspase; Histone Demethylase; Microtubule/Tubulin; Wee1
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Isoform
Caspase 3; Caspase 7
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Shipping Conditions
Room temperature
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Tubulin/LSD1-IN-1
Tubulin/LSD1-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.