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Tubulin/PARP-IN-1
Tubulin/PARP-IN-1
SKU:QM-0072756
Price on request
Quantity
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Product Details
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Description
Tubulin/PARP-IN-1 (compound 14) is a dual PARP-tubulin inhibitor with activity against endometrial cancer. Tubulin/PARP-IN-1 inhibits PARP and tubulin with IC50s of 74 nM (PARP1), 109 nM (PARP2), and 1.4 μM (Microtubule/Tubulin), respectively. Tubulin/PARP-IN-1 can induce apoptosis and autophagy and cause cell cycle arrest in the G2/M phase[1].
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Molecular Formula
C19H13FO3
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Molecular Weight
308.3
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Smiles
O=C1C=C(OC2=C1C=CC(C3=COC=C3)=C2)C4C=CC(F)=CC4
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Target
Microtubule/Tubulin; PARP
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Tubulin/PARP-IN-1
Tubulin/PARP-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.