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Tubulin polymerization-IN-77 [CAS 3023350-32-2]
Tubulin polymerization-IN-77 [CAS 3023350-32-2]
SKU:QM-0009581
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Product Details
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Description
Tubulin polymerization-IN-77 (Compound 15c) is a tubulin polymerization inhibitor that exerts anti-glioblastoma activity by inhibiting tubulin polymerization. Tubulin polymerization-IN-77 demonstrates significant blood-brain barrier permeability, effectively inducing G2/M phase arrest and triggering apoptosis in GBM cells, while also significantly inhibiting tumor cell migration[1].
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CAS Number
[3023350-32-2]
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Molecular Formula
C22H19BrF3NO7
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Molecular Weight
546.29
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Smiles
COC1=C(OCO2)C2=C(Br)C3=C1[C@@]([C@]4([H])C5=CC=C(OC)C(OC)=C5C(O4)=O)([H])N(CC3)C(F)(F)F
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Target
Microtubule/Tubulin
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Shipping Conditions
Room temperature
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Tubulin polymerization-IN-77 [CAS 3023350-32-2]
Tubulin polymerization-IN-77 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.