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5-HT7R antagonist 2 [CAS 1448808-50-1]
5-HT7R antagonist 2 [CAS 1448808-50-1]
SKU:QM-0108104
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Product Details
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Description
5-HT7R antagonist 2 (compound 4h) is a 5-HT7R antagonist that antagonizes the G protein and β-arrestin signaling pathways, with a Ki of 67 nM, the IC50 values in cAMP and Tango tests were 2.59 μM and 39.57 μM, respectively. 5-HT7R antagonist 2 has an effect on neurogenesis and can reduce repetitive behaviors related to autism spectrum disorder (ASD) and restore neurogenesis of ASD impairment[1].
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CAS Number
[1448808-50-1]
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Molecular Formula
C16H16N2O
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Molecular Weight
252.31
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Smiles
COC1=C(C2=CC=CC(C3=NCCN3)=C2)C=CC=C1
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Target
5-HT Receptor
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Isoform
5-HT7 Receptor; MUC3
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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5-HT7R antagonist 2 [CAS 1448808-50-1]
5-HT7R antagonist 2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.