8-Isoprostaglandin E2 [CAS 27415-25-4]
8-Isoprostaglandin E2 [CAS 27415-25-4]
SKU:QM-0061415
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Product Details
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Description
8-Isoprostaglandin E2 (iPE2-III) is a member of the isoprostane class of prostanoids. 8-Isoprostaglandin E2 acts at the receptor for thromboxane A2 (the TP) in vivo to induce vasoconstriction and platelet aggregation. 8-Isoprostaglandin E2 enhances receptor-activated NFkappa B ligand (RANKL) -dependent osteoclastic potential of marrow hematopoietic precursors via the cAMP pathway[1][2].
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CAS Number
[27415-25-4]
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Molecular Formula
C20H32O5
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Molecular Weight
352.47
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Smiles
CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C(C[C@H]1O)=O)C/C=C\CCCC(O)=O
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Target
Prostaglandin Receptor
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Isoform
TXA2/TP
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Purity
99
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Solubility
10 mM in DMSO|DMSO : ≥ 100mg/mL
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302-H360
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Precautions
P264-P270-P280-P330-P405-P501
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8-Isoprostaglandin E2 [CAS 27415-25-4]
8-Isoprostaglandin E2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.