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Aβ aggregation modulator-1 [CAS 71939-12-3]

Aβ aggregation modulator-1 [CAS 71939-12-3]

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SKU:QM-0134837

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  • Description

    Aβ aggregation modulator-1 is a stimulator of amyloid-β (Aβ) fibrillogenesis. Aβ aggregation modulator-1 binds hydrophobic residues in Aβ peptides and stabilizes β-sheet-rich protofibrils and fibrils. Aβ aggregation modulator-1 accelerates Aβ polymerization and reduces concentrations of small, toxic Aβ oligomers in heterogeneous aggregation reactions. Aβ aggregation modulator-1 suppresses long-term potentiation (LTP) inhibition by Aβ oligomers in hippocampal brain slices. Aβ aggregation modulator-1 can be used for the study of Alzheimer's disease (AD) [1].

  • CAS Number

    [71939-12-3]

  • Molecular Formula

    C24H15NO7

  • Molecular Weight

    429.38

  • Smiles

    O=C1C=C2OC3=CC(O)=C(C4=C(O)C=C(O)C=C4)C=C3N=C2C=C1C5=C(O)C=C(O)C=C5

  • Target

    Amyloid-β; Drug Derivative

  • Shipping Conditions

    Room temperature

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Aβ aggregation modulator-1 [CAS 71939-12-3]

Aβ aggregation modulator-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.