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A1/A3 AR antagonist 1 [CAS 312929-49-0]
A1/A3 AR antagonist 1 [CAS 312929-49-0]
SKU:QM-0066907
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Product Details
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Description
A1/A3 AR antagonist 1 (compound 10) is a potent adenosine 1 (A1) and adenosine 3 (A3) receptor dual antagonist with Kis of 36.7 nM, 25.4 nM and 1.47 nM for human A1, human A3 and rat A1, respectively. A1/A3 AR antagonist 1 can be used for researching kidney failure, inflammatory pulmonary diseases, and Alzheimer’s disease[1].
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CAS Number
[312929-49-0]
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Molecular Formula
C24H18N2O3S
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Molecular Weight
414.48
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Smiles
COC1=CC=C(C=C1)C(NC2=NC(C3=CC=CC=C3)=C(S2)C(C4=CC=CC=C4)=O)=O
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Target
Adenosine Receptor
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Isoform
Adenosine A1 receptor (A1R) ; Adenosine A3 receptor (A3R)
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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A1/A3 AR antagonist 1 [CAS 312929-49-0]
A1/A3 AR antagonist 1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.