ALDH1A inhibitor 673A [CAS 109437-62-9]
ALDH1A inhibitor 673A [CAS 109437-62-9]
SKU:QM-0077008-01
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Product Details
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Description
ALDH1A inhibitor 673A is an ALDH1A inhibitor with IC50s of 246 nM (ALDH1A1), 230 nM (ALDH1A2), 348 nM (ALDH1A3), respectively. ALDH1A inhibitor 673A has little or no inhibitory effect on other ALDH family members. ALDH1A inhibitor 673A induces necroptotic ovarian cancer stem-like cells (CSCs) death. ALDH1A inhibitor 673A induces DNA double stand breaks in cancer cells. ALDH1A inhibitor 673A can be used for the study of ovarian cancer[1][2][3].
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CAS Number
[109437-62-9]
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Molecular Formula
C15H13NO
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Molecular Weight
223.27
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Smiles
O=CC1=CC=C(N2CC3=C(C=CC=C3)C2)C=C1
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Target
Aldehyde Dehydrogenase (ALDH) ; Mitochondrial Metabolism; Necroptosis
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Purity
99.15
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Solubility
DMSO : 29.17 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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ALDH1A inhibitor 673A [CAS 109437-62-9]
ALDH1A inhibitor 673A is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.