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ALK/ROS1-IN-1 [CAS 2365497-07-8]
ALK/ROS1-IN-1 [CAS 2365497-07-8]
SKU:QM-0061541
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Product Details
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Description
ALK/ROS1-IN-1 (compound 2e) is a potent and selective anti crizotinib-resistant ALK/ROS1 dual inhibitor, with IC50s of 0.174 μM and 0.530 μM for ALK and ROS1 enzyme, respectively.
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CAS Number
[2365497-07-8]
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Molecular Formula
C30H35F3N6O3
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Molecular Weight
584.63
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Smiles
O=C([C@H]1CCCN(C2=CC(NC3=CC=C(N4CCNCC4)C=C3OC)=NC=C2)C1)NCC5=CC=C(OC(F)(F)F)C=C5
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Target
Anaplastic lymphoma kinase (ALK) ; ROS Kinase
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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ALK/ROS1-IN-1 [CAS 2365497-07-8]
ALK/ROS1-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.