AMPA receptor modulator-9 [CAS 1204572-46-2]
AMPA receptor modulator-9 [CAS 1204572-46-2]
SKU:QM-0015028
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Product Details
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Description
AMPA receptor modulator-9 is an orally active, selective positive allosteric modulator (PAM) of AMPARs with blood-brain barrier penetration. AMPA receptor modulator-9 selectively potentiates AMPAR activity in human and rat models, with an EC2x value of 0.96 μM in rat embryonic cortex primary neurons. AMPA receptor modulator-9 upregulates BDNF protein expression in rat primary cortical neuronal cultures. AMPA receptor modulator-9 enhances AMPA-mediated excitatory postsynaptic responses in rat and mice. AMPA receptor modulator-9 can be used for the study of cognitive disorders[1].
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CAS Number
[1204572-46-2]
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Molecular Formula
C10H10Cl2N2O2S
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Molecular Weight
293.17
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Smiles
O=S1(NCN(C2=CC(Cl)=C(C=C21)Cl)C3CC3)=O
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Target
IGluR
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Isoform
AMPA Receptor
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Shipping Conditions
Room temperature
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AMPA receptor modulator-9 [CAS 1204572-46-2]
AMPA receptor modulator-9 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.