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Androgen receptor antagonist 4 [CAS 354815-43-3]
Androgen receptor antagonist 4 [CAS 354815-43-3]
SKU:QM-0066527
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Product Details
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Description
Androgen receptor antagonist 4 (Compound AT2) is an androgen receptor (AR) antagonist with an IC50 of 0.15 μM. Androgen receptor antagonist 4 efficiently antagonizes AR transcriptional activity, suppresses downstream target gene of AR, and blocks the DHT-induced AR nuclear translocation. Androgen receptor antagonist 4 shows anticancer activities[1].
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CAS Number
[354815-43-3]
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Molecular Formula
C22H18ClN
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Molecular Weight
331.84
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Smiles
ClC1=CC=C(C2NC3=C(C4=CC=CC=C4C=C3)C5C2CC=C5)C=C1
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Target
Androgen Receptor
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Androgen receptor antagonist 4 [CAS 354815-43-3]
Androgen receptor antagonist 4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.