Anti-osteoporosis agent-11 [CAS 2869099-50-1]
Anti-osteoporosis agent-11 [CAS 2869099-50-1]
SKU:QM-0104288
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Product Details
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Description
Anti-osteoporosis agent-11 (compound 3k) is an anti-osteoporosis compound targeting osteoclasts. Anti-osteoporosis agent-11 has the most significant inhibitory effect on osteoclast differentiation, with an IC50 value of 0.36 μM. In addition, Anti-osteoporosis agent-11 inhibits osteoclast formation, bone resorption, and the expression of osteoclast-specific genes by blocking rankl-induced mitogen-activated protein kinase (MAPK) and NF-κB signaling pathways[1].
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CAS Number
[2869099-50-1]
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Molecular Formula
C23H17NO2Se2
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Molecular Weight
497.31
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Smiles
O=C1C([Se]C2=CC=CC=C2)=C(C(N1CC3=CC=CC=C3)=O)[Se]C4=CC=CC=C4
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Target
NF-κB; p38 MAPK; RANKL/RANK
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Shipping Conditions
Room temperature
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Anti-osteoporosis agent-11 [CAS 2869099-50-1]
Anti-osteoporosis agent-11 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.