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AR antagonist 11 [CAS 3005979-40-5]
AR antagonist 11 [CAS 3005979-40-5]
SKU:QM-0011499
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Product Details
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Description
AR antagonist 11 (Compound c2) is a selective AR antagonist with an IC50 of 0.019 μM. AR antagonist 11 is also effective against ARF877L/T878A mutant (IC50: 1.03 μM) . AR antagonist 11 inhibits LNCaP cell proliferation and reduces PSA protein expression (IC50: 0.54 μM) . AR antagonist 11 can be used for research of prostate cancer (PCa) [1].
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CAS Number
[3005979-40-5]
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Molecular Formula
C20H17ClN2O
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Molecular Weight
336.81
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Smiles
ClC(C=C1)=CC=C1[C@@H]([C@@H]2[C@H]3OCC2)NC4=C3C5=CC=CN=C5C=C4
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Target
Androgen Receptor; Ser/Thr Protease
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Shipping Conditions
Room temperature
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AR antagonist 11 [CAS 3005979-40-5]
AR antagonist 11 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.