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ATM Inhibitor-4 [CAS 2769140-74-9]

ATM Inhibitor-4 [CAS 2769140-74-9]

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SKU:QM-0065932

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  • Description

    ATM Inhibitor-4 (compound 39) is a potent and selective ATM inhibitor, with an IC50 of 0.32 nM. ATM Inhibitor-4 shows stronger inhibition of PI3K kinases family. ATM Inhibitor-4 shows a full inhibition of mTOR at 1 μM. ATM Inhibitor-4 exhibits favorable metabolic stability[1].

  • CAS Number

    [2769140-74-9]

  • Molecular Formula

    C26H29FN6O3

  • Molecular Weight

    492.55

  • Smiles

    COCCN1C(N(C2=C1C3=CC(C4=CC=C(C=C4)NC(NCCN5CC(C5)F)=O)=CC=C3N=C2)C)=O

  • Target

    ATM/ATR; mTOR; PI3K

  • Isoform

    ATM; mTOR; PI3K

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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ATM Inhibitor-4 [CAS 2769140-74-9]

ATM Inhibitor-4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.