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ATX inhibitor 15 [CAS 2484811-52-9]
ATX inhibitor 15 [CAS 2484811-52-9]
SKU:QM-0065290
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Product Details
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Description
ATX inhibitor 15 (compound 30), a indole-based carbamate derivative, is a potent autotaxin (ATX) inhibitor with an IC50 of 2.17 nM. ATX inhibitor 15 inhibits in vivo ATX and the gene expression of pro-fibrotic factors. ATX inhibitor 15 has lung protection effects in Bleomycin challenged mice lung fibrosis model[1].
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CAS Number
[2484811-52-9]
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Molecular Formula
C27H32ClN5O4S
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Molecular Weight
558.09
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Smiles
O=C(NCC1=CC=C(C(Cl)=C1)OC)NC2=CN(CC)C3=C2C=C(C4=NC(CN(CCO)CCO)=CS4)C=C3
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Target
Phosphodiesterase (PDE)
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Isoform
Autotaxin
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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ATX inhibitor 15 [CAS 2484811-52-9]
ATX inhibitor 15 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.