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ATX inhibitor 25 [CAS 2951100-44-8]
ATX inhibitor 25 [CAS 2951100-44-8]
SKU:QM-0008707
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Product Details
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Description
ATX inhibitor 25 (Compound 29) is an orally active Autotaxin inhibitor with an IC50 of 1.08 nM. ATX inhibitor 25 exhibits excellent in vitro metabolic stability, with a t1/2 of more than 170 minutes. In the bleomycin -induced pulmonary fibrosis mouse model, orally administered ATX inhibitor 25 shows anti-fibrotic effects[1].
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CAS Number
[2951100-44-8]
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Molecular Formula
C23H20ClFN4O5
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Molecular Weight
486.88
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Smiles
CC1=C(C(NC2=CC(C(O)=O)=C(F)C=C2)=O)C3=CC(OC)=C(Cl)C=C3N1C4=CN(COC)N=C4
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Target
Phosphodiesterase (PDE)
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Shipping Conditions
Room temperature
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ATX inhibitor 25 [CAS 2951100-44-8]
ATX inhibitor 25 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.