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ATX inhibitor 26 [CAS 2940248-11-1]
ATX inhibitor 26 [CAS 2940248-11-1]
SKU:QM-0011564
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Product Details
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Description
ATX inhibitor 26 is an Autotaxin (ATX) inhibitor with an IC50 of 57 nM in human plasma. ATX inhibitor 26 inhibits cell migration and collagen gel contraction. ATX inhibitor 26 has significant anti-fibrotic effects, reducing collagen deposition in a Bleomycin (BLM) -induced pulmonary fibrosis model[1].
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CAS Number
[2940248-11-1]
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Molecular Formula
C18H19Cl2N7O3
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Molecular Weight
452.29
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Smiles
ClC1=CC(Cl)=CC(COC(N2CCC(C3=NN=C(NCC4=CN=NN4)O3)CC2)=O)=C1
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Target
ERK; JNK; p38 MAPK; Phosphodiesterase (PDE)
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Isoform
Autotaxin
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Shipping Conditions
Room temperature
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ATX inhibitor 26 [CAS 2940248-11-1]
ATX inhibitor 26 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.