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ATX inhibitor 27 [CAS 2023027-81-6]
ATX inhibitor 27 [CAS 2023027-81-6]
SKU:QM-0011585
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Product Details
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Description
ATX inhibitor 27 (Compound 31) is an ATX inhibitor. The IC50 values of ATX inhibitor 27 against human autotaxin (hATX) and lysophosphatidylcholine (LPC) are 13 nM and 23 nM, respectively. ATX inhibitor 27 reduces LPA levels in vivo by inhibiting ATX enzyme. ATX inhibitor 27 can be used in the study of ATX-LPA-related diseases such as inflammation, neurodegenerative diseases and cancer[1].
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CAS Number
[2023027-81-6]
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Molecular Formula
C26H26ClN5O3
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Molecular Weight
491.97
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Smiles
CC(N1CCC(C2=CC3=C(N=CN(CC(N(C)CC4=CC=C(C#N)C(Cl)=C4)=O)C3=O)C=C2)CC1)=O
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Target
LPL Receptor; Phosphodiesterase (PDE)
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Shipping Conditions
Room temperature
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ATX inhibitor 27 [CAS 2023027-81-6]
ATX inhibitor 27 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.